Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001117 | 0.88 | LMNA (0.52) | LMNAHPGDMAPTRAB9AL3MBTL1 | |
| SCHEMBL6815544 | 0.85 | LMNA (0.57) | LMNAHPGDMAPTRAB9AL3MBTL1 | |
| SCHEMBL2575159 | 0.82 | MAPT (0.64) | LMNAHPGDMAPTRAB9AL3MBTL1 | |
| SCHEMBL3999257 | 0.80 | RXRA (0.56) | HPGDMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6158387 | 0.80 | TSHR (0.67) | LMNAHPGDMAPTRAB9AL3MBTL1 | |
| SCHEMBL2842635 | 0.80 | HPGD (0.57) | LMNAHPGDMAPTRAB9AL3MBTL1 | |
| SCHEMBL6819480 | 0.80 | LMNA (0.57) | LMNAHPGDMAPTRAB9AL3MBTL1 | |
| SCHEMBL11844159 | 0.79 | MAPK1 (0.46) | MAPTRAB9AL3MBTL1NPC1GAA | |
| SCHEMBL2854822 | 0.79 | HPGD (0.56) | LMNAHPGDMAPTRAB9AL3MBTL1 | |
| SCHEMBL28085734 | 0.79 | MTNR1A (0.46) | LMNAHPGDMAPTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344780-A1 | GLUCOPYRANOSYLOXYBENZYL BENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-09-17 | — | — | EP | disclosed |