Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607728 | 0.86 | TDP1 (0.58) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL14768871 | 0.85 | TDP1 (0.66) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL21538018 | 0.85 | TDP1 (0.66) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL6234683 | 0.84 | L3MBTL1 (0.49) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL23408894 | 0.84 | TDP1 (0.51) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL6234751 | 0.83 | KMT2A (0.59) | POLBTDP1KMT2AL3MBTL1TSHR | |
| SCHEMBL20305864 | 0.83 | TDP1 (0.54) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL24576746 | 0.83 | TDP1 (0.54) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL14788645 | 0.83 | TDP1 (0.54) | POLBTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL24414100 | 0.82 | TDP1 (0.50) | POLBTDP1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113273575-B | Ternary weeding composition containing pyrimidine benzyl carboxylate compounds and application thereof | 江苏清原农冠杂草防治有限公司 | 2022-02-11 | — | — | CN | claimed |
| CN-112841200-B | Weeding composition containing pyrimidine benzyl carboxylate compounds and pigment synthesis inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-112841199-B | Herbicidal composition containing pyrimidine benzyl carboxylate compound and lipid synthesis inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-112841196-B | Weeding composition containing pyrimidine benzyl carboxylate compounds and application thereof | 江苏清原农冠杂草防治有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-112841197-B | Herbicidal composition containing pyrimidine benzyl carboxylate compound and PSII inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-112841202-B | Herbicidal composition containing pyrimidine benzyl carboxylate compound and ALS inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-112841198-B | Herbicidal compositions comprising benzyl pyrimidinecarboxylates and microtubule assembly/VLCFA inhibitors and uses thereof | 江苏清原农冠杂草防治有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-112841195-B | Herbicidal composition containing pyrimidine benzyl carboxylate compounds and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-112841201-B | Weeding composition containing pyrimidine benzyl carboxylate compounds and PPO inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-113273575-A | Ternary weeding composition containing pyrimidine benzyl carboxylate compounds and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-08-20 | — | — | CN | claimed |
| CN-112841197-A | Herbicidal composition containing pyrimidine benzyl carboxylate compound and PSII inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112841202-A | Herbicidal composition containing pyrimidine benzyl carboxylate compound and ALS inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112841196-A | Weeding composition containing pyrimidine benzyl carboxylate compounds and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112841195-A | Herbicidal composition containing pyrimidine benzyl carboxylate compounds and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112841200-A | Weeding composition containing pyrimidine benzyl carboxylate compounds and pigment synthesis inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112841199-A | Herbicidal composition containing pyrimidine benzyl carboxylate compound and lipid synthesis inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112841201-A | Weeding composition containing pyrimidine benzyl carboxylate compounds and PPO inhibitor and application thereof | 江苏清原农冠杂草防治有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112841198-A | Herbicidal compositions comprising benzyl pyrimidinecarboxylates and microtubule assembly/VLCFA inhibitors and uses thereof | 江苏清原农冠杂草防治有限公司 | 2021-05-28 | — | — | CN | claimed |
| US-12391698-B2 | Substituted piperidines and piperazines and methods for the treatment of CNS disorders | SUVEN LIFE SCIENCES LIMITED (IN) | 2025-08-19 | — | — | US | disclosed |
| WO-2002064598-A1 | THIENO'2,3-D PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391698-B2 | Substituted piperidines and piperazines and methods for the treatment of CNS disorders | GRIN2C, SLC1A2, CNR2 | POLB 2880/4885TDP1 2450/4885KMT2A 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.