SCHEMBL7101552

SCHEMBL7101552

CCCCCC=CC(=O)OCc1cnc(C)c(O)c1COC(=O)C=CCCCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SGPL1 O95470 2/20 0.43
MAPT P10636 2/20 0.41
ALDH1A1 P00352 3/20 0.38
PSMB11 A5LHX3 1/20 0.37
PSMA7 O14818 1/20 0.37
PSMB1 P20618 1/20 0.37
PSMA1 P25786 1/20 0.37
PSMA2 P25787 1/20 0.37
PSMA3 P25788 1/20 0.37
PSMA4 P25789 1/20 0.37
PSMB8 P28062 1/20 0.37
PSMB9 P28065 1/20 0.37
PSMA5 P28066 1/20 0.37
PSMB4 P28070 1/20 0.37
PSMB6 P28072 1/20 0.37
PSMB5 P28074 1/20 0.37
PSMB10 P40306 1/20 0.37
PSMB3 P49720 1/20 0.37
PSMB2 P49721 1/20 0.37
PSMA6 P60900 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30542180 1.00 SGPL1 (0.43) SGPL1MAPTALDH1A1PSMB11PSMA7
SCHEMBL31190161 0.78 ALDH1A1 (0.45) SGPL1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL9697296 0.74 DGKA (0.41) SGPL1ALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL1546007 0.73 KDM4E (0.47) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL20143334 0.72 HPGD (0.50) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL27487508 0.70 MAPT (0.70) MAPTALDH1A1HSD17B10LMNA
SCHEMBL872986 0.70 MAPT (0.70) MAPTALDH1A1HSD17B10LMNA
SCHEMBL872985 0.70 MAPT (0.70) MAPTALDH1A1HSD17B10LMNA
SCHEMBL25406757 0.69 MAPT (0.68) MAPTALDH1A1HSD17B10LMNA
SCHEMBL11795363 0.69 MAPT (0.68) MAPTALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0981318-B1 COMPOSITION FOR TREATING HAIR OREAL (FR) 2003-07-09 EP claimed
EP-2654665-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA Pharma Gesellschaft für die Entwicklung und Vermarktung pharmazeutischer Produkte mbH (DE) 2013-10-30 EP disclosed
WO-2012083906-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FÜR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2012-06-28 WO disclosed