Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10978703 | 0.80 | TAAR1 (0.61) | CA2TAAR1ALDH1A1TSHRTDP1 | |
| SCHEMBL144360 | 0.80 | ALDH1A1 (0.58) | CA2TAAR1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL7862032 | 0.79 | ALDH1A1 (0.42) | CA2TAAR1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL56491 | 0.79 | CA2 (0.58) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL10342309 | 0.79 | TAAR1 (0.48) | CA2TAAR1GABRA1GABRB2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11279791 | 0.78 | PTPN22 (0.40) | CA2TAAR1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL1833403 | 0.77 | CA2 (0.56) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL8805196 | 0.76 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL30634154 | 0.76 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL4746864 | 0.76 | CA2 (0.54) | CA2GABRA1GABRB2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627766-B2 | Use of phenylenediamines and hindered phenols to inhibit polymer formation during the manufacture of acrylonitrile | BAKER HUGHES INCORPORATED | 2003-09-30 | — | — | US | claimed |
| US-6608226-B1 | Low cost | BAKER HUGHES INCORPORATED | 2003-08-19 | — | — | US | claimed |
| US-20030109739-A1 | Use of phenylenediamines and hindered phenols to inhibit polymer formation during the manufacture of acrylonitrile | REID DWIGHT K (US) | 2003-06-12 | — | — | US | claimed |
| US-6025515-A | STABILIZING WITH 2,6-DI-TERT-BUTYL-4-METHYLPHENOL, 3,3,3',3'-TETRAMETHYL-1,1'-SPIROBISINDANE-5,5',6,6'-TETROL, 2,6-DI-TERT-BUTYLPHENOL, 2,4,6-TRI-TERT-BUTYLPHENOL, 2,6-DI-TERT-BUTYL-4-AMINEPHENOL, 2,6-DI-TERT-BUTYLPHENOL | BAKER HUGHES INCORPORATED (US) | 2000-02-15 | — | — | US | claimed |
| US-6627766-B2 | Use of phenylenediamines and hindered phenols to inhibit polymer formation during the manufacture of acrylonitrile | BAKER HUGHES INCORPORATED | 2003-09-30 | — | — | US | disclosed |
| US-6608226-B1 | Low cost | BAKER HUGHES INCORPORATED | 2003-08-19 | — | — | US | disclosed |
| US-20030109739-A1 | Use of phenylenediamines and hindered phenols to inhibit polymer formation during the manufacture of acrylonitrile | REID DWIGHT K (US) | 2003-06-12 | — | — | US | disclosed |
| US-6025515-A | STABILIZING WITH 2,6-DI-TERT-BUTYL-4-METHYLPHENOL, 3,3,3',3'-TETRAMETHYL-1,1'-SPIROBISINDANE-5,5',6,6'-TETROL, 2,6-DI-TERT-BUTYLPHENOL, 2,4,6-TRI-TERT-BUTYLPHENOL, 2,6-DI-TERT-BUTYL-4-AMINEPHENOL, 2,6-DI-TERT-BUTYLPHENOL | BAKER HUGHES INCORPORATED (US) | 2000-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109739-A1 | Use of phenylenediamines and hindered phenols to inhibit polymer formation during the manufacture of acrylonitrile | PNN, PNMT, PAH | CA2 3603/4885TAAR1 1603/4885GABRA1 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.