Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101588 | 0.94 | RAB9A (0.40) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL2837319 | 0.83 | MAPT (0.42) | RAB9AMAPTMEN1KMT2AADRA1D | |
| SCHEMBL2833521 | 0.82 | ITGB3 (0.42) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL2839637 | 0.81 | RAB9A (0.44) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL2835959 | 0.80 | CHRNB2 (0.47) | RAB9ANPC1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2837227 | 0.77 | ITGB3 (0.43) | RAB9AMAPTMEN1KMT2A | |
| SCHEMBL2838982 | 0.77 | MAPK1 (0.49) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL2841296 | 0.75 | ITGB3 (0.44) | MAPT | |
| SCHEMBL2832143 | 0.75 | ITGB3 (0.45) | RAB9ANPC1KMT2A | |
| SCHEMBL2836433 | 0.74 | MAPK1 (0.51) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282602-A1 | PROPANOIC ACID DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | Pharmacia Italia S.p.A. (IT) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087840-A1 | PROPANOIC ACID DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA ITALIA S.P.A. (IT) | 2001-11-22 | — | — | WO | disclosed |