Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578889 | 0.92 | AAK1 (0.35) | HDAC6HDAC1HDAC2AAK1MMP13 | |
| SCHEMBL618364 | 0.92 | AAK1 (0.35) | HDAC6HDAC1HDAC2AAK1MMP13 | |
| SCHEMBL15208119 | 0.92 | AAK1 (0.35) | HDAC6HDAC1HDAC2AAK1MMP13 | |
| SCHEMBL27685428 | 0.91 | AAK1 (0.34) | HDAC6HDAC1HDAC2AAK1MMP13 | |
| SCHEMBL74866 | 0.78 | AAK1 (0.36) | HDAC6HDAC1HDAC2AAK1MMP13 | |
| SCHEMBL2837457 | 0.76 | HDAC6 (0.35) | HDAC6HDAC1HDAC2 | |
| SCHEMBL31716095 | 0.75 | L3MBTL1 (0.38) | HDAC6AAK1 | |
| SCHEMBL31716325 | 0.75 | ALDH1A1 (0.35) | HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL25165441 | 0.74 | HDAC6 (0.33) | HDAC6HDAC1HDAC2 | |
| SCHEMBL2968992 | 0.74 | AAK1 (0.36) | HDAC6HDAC1HDAC2AAK1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030087915-A1 | Pharmaceutical compositions and methods for use | DULL GARY MAURICE (US) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087915-A1 | Pharmaceutical compositions and methods for use | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP4B1, HTR3E | HDAC6 1411/4885HDAC1 3015/4885HDAC2 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.