Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733776 | 0.78 | EPHX2 (0.53) | EPHX2MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8509315 | 0.75 | HDAC4 (0.57) | MAPTL3MBTL1HTTCYP3A4CYP1A2 | |
| SCHEMBL6013464 | 0.75 | MAOB (0.59) | EPHX2MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11458040 | 0.75 | L3MBTL1 (0.66) | EPHX2MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1561387 | 0.75 | MAPT (0.70) | EPHX2MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11517424 | 0.74 | MEN1 (0.54) | MAPTALDH1A1SMN1; SMN2L3MBTL1CYP3A4 | |
| SCHEMBL1689206 | 0.74 | EPHX2 (0.68) | EPHX2MAPTSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL8530977 | 0.74 | MAPT (0.53) | EPHX2MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4526488 | 0.73 | KDM1A (0.49) | EPHX2MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| Water SCHEMBL9506366 | 0.73 | MAOB (0.58) | EPHX2MAPTALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892813-A4 | RECOMBINANT PREPARATION OF CALCITONIN FRAGMENTS AND USE THEREOF IN THE PREPARATION OF CALCITONIN AND RELATED ANALOGS | BIONEBRASKA INC (US) | 2003-02-05 | — | — | EP | claimed |
| EP-0892813-A1 | RECOMBINANT PREPARATION OF CALCITONIN FRAGMENTS AND USE THEREOF IN THE PREPARATION OF CALCITONIN AND RELATED ANALOGS | BIONEBRASKA, INC. (US) | 1999-01-27 | — | — | EP | claimed |
| WO-1997029127-A1 | RECOMBINANT PREPARATION OF CALCITONIN FRAGMENTS AND USE THEREOF IN THE PREPARATION OF CALCITONIN AND RELATED ANALOGS | BIONEBRASKA, INC. (US) | 1997-08-14 | — | — | WO | claimed |
| WO-2003099852-A2 | PEPTIDE DERIVATIZATION PROCESS | RESTORAGEN INC. (US) | 2003-12-04 | — | — | WO | disclosed |