Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101628 | 1.00 | GABBR2 (0.41) | GABBR2GABBR1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL1859129 | 0.82 | GABBR2 (0.52) | GABBR2GABBR1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL6728558 | 0.79 | CCR5 (0.50) | GABBR2GABBR1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL9641227 | 0.78 | NR1I2 (0.49) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL5678177 | 0.78 | NR1I2 (0.49) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL9641509 | 0.78 | NR1I2 (0.49) | GABBR2GABBR1ALDH1A1 | |
| SCHEMBL27509017 | 0.77 | GABBR2 (0.47) | GABBR2GABBR1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL10613677 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4ELMNAPOLB | |
| SCHEMBL4601734 | 0.75 | GABBR2 (0.69) | GABBR2GABBR1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL28614078 | 0.75 | GABBR2 (0.42) | GABBR2GABBR1ALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341799-A1 | P-CHIRALE BISPHOSPHOLANE LIGANDS, THEIR TRANSITION METAL COMPLEXES | Warner-Lambert Company LLC (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002048161-A1 | P-CHIRALE BISPHOSPHOLANE LIGANDS, THEIR TRANSITION METAL COMPLEXES | WARNER-LAMBERT COMPANY LLC (US) | 2002-06-20 | — | — | WO | disclosed |