Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100519 | 0.81 | LMNA (0.50) | AOC3ALDH1A1KMT2AMEN1 | |
| SCHEMBL16124230 | 0.81 | LMNA (0.50) | AOC3ALDH1A1KMT2AMEN1 | |
| SCHEMBL15050822 | 0.75 | AOC3 (0.44) | AOC3ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL15050516 | 0.75 | AOC3 (0.44) | AOC3ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL15050517 | 0.75 | AOC3 (0.44) | AOC3ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL15050518 | 0.75 | AOC3 (0.44) | AOC3ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL15050823 | 0.75 | AOC3 (0.44) | AOC3ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL30648596 | 0.73 | MAPT (0.40) | ALDH1A1CYP19A1 | |
| SCHEMBL31507797 | 0.73 | AOC3 (0.43) | AOC3ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL12224067 | 0.73 | AOC3 (0.43) | AOC3ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809647-B1 | CHIRAL ORGANOMETALLIC COMPOUNDS | AVECIA LTD (GB) | 2003-09-10 | — | — | EP | disclosed |
| US-5929266-A | ZIRCONIUM, HAFNIUM, TITANIUM CYCLOPENTADIENE COMPOUNDS USEFUL IN ASYMMETRIC SYNTHESIS | ZENECA LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |
| EP-0809647-A1 | CHIRAL ORGANOMETALLIC COMPOUNDS | ZENECA LIMITED (GB) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025420-A1 | CHIRAL ORGANOMETALLIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-08-22 | — | — | WO | disclosed |