SCHEMBL30648596

SCHEMBL30648596

C=C[C@@H](CSc1ccccc1)[C@@H](O)c1ccc(F)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
ALDH1A1 P00352 5/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
HTT P42858 2/20 0.35
LMNA P02545 2/20 0.35
CYP19A1 P11511 2/20 0.35
MTNR1A P48039 3/20 0.33
MTNR1B P49286 3/20 0.33
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CNR2 P34972 1/20 0.32
MAPK1 P28482 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30648565 0.90 MAOA (0.41) ALDH1A1MAOAMAOBLMNAMTNR1A
SCHEMBL30648577 0.87 CYP3A4 (0.39) ALDH1A1MAOAMAOBHTTLMNA
SCHEMBL29155615 0.86 MAOA (0.39) MAPTALDH1A1SMN1; SMN2MAOAMAOB
SCHEMBL30648575 0.86 MMP2 (0.40) MAOAMAOBMTNR1AMTNR1BGAA
SCHEMBL29155614 0.86 MAOA (0.39) MAPTALDH1A1SMN1; SMN2MAOAMAOB
SCHEMBL30648593 0.84 KDM4E (0.42) ALDH1A1MAOAMAOBLMNAMTNR1A
SCHEMBL30648590 0.82 ALDH1A1 (0.40) MAPTALDH1A1SMN1; SMN2MAOAMAOB
SCHEMBL30648578 0.78 TSHR (0.47) MAPTALDH1A1SMN1; SMN2HTTLMNA
SCHEMBL30648604 0.76 ALDH1A1 (0.40) MAPTALDH1A1SMN1; SMN2HTTLMNA
SCHEMBL30648581 0.74 TSHR (0.36) ALDH1A1MAOAMAOBHTTMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304081-A Method for synthesizing homoallylic alcohol compound by synergistic catalysis of visible light and titanium 河南师范大学 2023-12-29 CN disclosed