Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101905 | 1.00 | ACHE (0.50) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7103899 | 0.95 | ADRA1A (0.49) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7102283 | 0.95 | ADRA1A (0.49) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7100693 | 0.94 | ADRA1A (0.48) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7102137 | 0.94 | ADRA1A (0.48) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7098299 | 0.89 | DRD3 (0.51) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| SCHEMBL7099317 | 0.89 | DRD3 (0.51) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| SCHEMBL7100743 | 0.85 | DRD3 (0.58) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| SCHEMBL7098164 | 0.85 | DRD3 (0.58) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| SCHEMBL7097644 | 0.85 | DRD3 (0.58) | ADRA1ADRD2DRD4HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |