SCHEMBL710195

SCHEMBL710195

c1cnc2ccc3ccnnc3c2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
MAPT P10636 3/20 0.54
KDM4E B2RXH2 2/20 0.54
CYP3A4 P08684 2/20 0.53
HSP90AA1 P07900 3/20 0.43
HTT P42858 3/20 0.43
HIF1A Q16665 2/20 0.43
CCR1 P32246 2/20 0.43
CCR5 P51681 2/20 0.43
CCR8 P51685 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GMNN O75496 1/20 0.43
TP53 P04637 1/20 0.43
MMP2 P08253 1/20 0.43
CYP2D6 P10635 1/20 0.43
MMP9 P14780 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
MMP8 P22894 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13859946 0.86 LMNA (0.54) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL157930 0.85 LMNA (0.61) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL21001801 0.85 LMNA (0.61) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL31143538 0.84 LMNA (0.59) LMNAMAPTKDM4ECYP3A4HSP90AA1
Naphthalene SCHEMBL28746803 0.82 LMNA (0.58) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL22045599 0.80 PKM (0.46) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL8313 0.80 LMNA (1.00) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL6513577 0.80 LMNA (1.00) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL5804134 0.80 LMNA (0.59) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL11055097 0.79 LMNA (0.48) LMNAMAPTKDM4ECYP3A4HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006091799-A2 HIGH BANDGAP ARYLENE POLYMERS SUMATION CO. LTD. (JP) 2006-08-31 WO claimed
WO-2025020676-A1 ORGANIC ELECTROLUMINESCENT DEVICE HAVING HIGH PERFORMANCE AND COMPOUND THEREOF 京东方科技集团股份有限公司 2025-01-30 WO disclosed
CN-118812533-A Azapyrazinophenanthroline small-molecule organic corrosion inhibitor and preparation method thereof 洛阳船舶材料研究所(中国船舶集团有限公司第七二五研究所) 2024-10-22 CN disclosed
CN-118005672-A Synthesis method of silicon-containing electron transport material 夏禾科技(江苏)有限公司 2024-05-10 CN disclosed
CN-115322215-B Synthesis method of silicon-containing electron transport material 夏禾科技(江苏)有限公司 2024-03-19 CN disclosed
CN-115322215-A Synthetic method of silicon-containing electron transport material 夏禾科技(江苏)有限公司 2022-11-11 CN disclosed
CN-113387892-B Imidazole heterocyclic derivative containing nitrogen mustard and preparation method and application thereof 广东海洋大学 2022-02-01 CN disclosed
CN-113387892-A Imidazole heterocyclic derivative containing nitrogen mustard and preparation method and application thereof 广东海洋大学 2021-09-14 CN disclosed
CN-113135961-A Organometallic compound, organic light-emitting device including the organometallic compound, and electronic apparatus including the organic light-emitting device 三星电子株式会社 2021-07-20 CN disclosed
EP-3310795-B1 POLYMERIZATION OF SILYL- AND FLUORO-CONTAINING MONOMERS SCRIPPS RESEARCH INST (US) 2021-06-16 EP disclosed
WO-2001085732-A1 PYRIDOBENZODIAZINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KYORIN PHARMACEUTICAL CO., LTD. (JP) 2001-11-15 WO disclosed
EP-1015450-A1 NOVEL PYRIDAZINE COMPOUNDS AstraZeneca UK Limited (GB) 2000-07-05 EP disclosed
EP-1015450-A1 NOVEL PYRIDAZINE COMPOUNDS AstraZeneca UK Limited (GB) 2000-07-05 EP disclosed
CN-1219934-A Novel pyridazine compounds ASTRA PHARMA PROD (GB) 1999-06-16 CN disclosed
WO-1997045428-A1 NOVEL PYRIDAZINE COMPOUNDS ASTRA PHARMACEUTICALS LTD. (GB) 1997-12-04 WO disclosed
WO-1997045428-A1 NOVEL PYRIDAZINE COMPOUNDS ASTRA PHARMACEUTICALS LTD. (GB) 1997-12-04 WO disclosed
EP-0470578-B1 Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same WAKUNAGA SEIYAKU KK (JP) 1996-11-06 EP disclosed
US-5399553-A Oral absorbability WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1995-03-21 US disclosed
US-5254685-A Tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1993-10-19 US disclosed
EP-0470578-A1 Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1992-02-12 EP disclosed