Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101373 | 0.90 | MAOB (0.66) | NR1H4MAPTNPC1LMNARAB9A | |
| SCHEMBL7103789 | 0.85 | MAPT (0.74) | NR1H4MAPTNPC1LMNARAB9A | |
| SCHEMBL1723180 | 0.82 | MAPT (1.00) | NR1H4MAPTNPC1LMNARAB9A | |
| SCHEMBL1723179 | 0.82 | MAPT (1.00) | NR1H4MAPTNPC1LMNARAB9A | |
| SCHEMBL7096880 | 0.82 | NR1H4 (0.74) | NR1H4MAPTNPC1LMNARAB9A | |
| SCHEMBL5915411 | 0.81 | NR1H4 (0.66) | NR1H4MAPTNPC1LMNARAB9A | |
| SCHEMBL5915830 | 0.81 | NR1H4 (0.66) | NR1H4MAPTNPC1LMNARAB9A | |
| SCHEMBL28796161 | 0.81 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7099543 | 0.80 | NR1H4 (0.70) | NR1H4MAPTNPC1LMNARAB9A | |
| SCHEMBL8994729 | 0.78 | MAPT (0.70) | MAPTNPC1LMNARAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | claimed |