Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464425 | 0.75 | HPGD (0.49) | HPGDKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL5881010 | 0.72 | ALDH1A1 (0.41) | HPGDKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL421283 | 0.70 | LMNA (0.39) | HPGDKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL464396 | 0.69 | LMNA (0.41) | HPGDKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL13030806 | 0.69 | LMNA (0.39) | HPGDKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL13569377 | 0.69 | ALDH1A1 (0.46) | HPGDKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL10800035 | 0.68 | AKT1 (0.44) | KMT2AMEN1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL12786453 | 0.67 | EHMT2 (0.45) | HPGDKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL7691009 | 0.67 | CYP3A4 (0.49) | KMT2ATSHRMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4757038 | 0.66 | EHMT2 (0.52) | HPGDKMT2ATSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |