SCHEMBL7102181

SCHEMBL7102181

COc1cc(OC)c(C=CC(=O)c2ccccc2N)c(OC)c1

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 8/20 0.63
AURKA O14965 1/20 0.57
MAOA P21397 2/20 0.56
CHRNA7 P36544 1/20 0.56
MAPT P10636 4/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
ABCB1 P08183 1/20 0.53
TNFRSF1A P19438 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7097152 0.87 ABCG2 (0.63) ABCG2AURKAMAPTMEN1KMT2A
SCHEMBL7098090 0.84 MAPT (0.71) ABCG2CHRNA7MAPTMEN1NPC1
SCHEMBL7096821 0.82 PDE4A (0.70) ABCG2MAPT
SCHEMBL7102175 0.82 ABCG2 (0.60) ABCG2AURKAMAOACHRNA7MAPT
SCHEMBL4456570 0.80 ABCG2 (0.76) ABCG2MAOACHRNA7MAPTMEN1
SCHEMBL4610668 0.80 ABCG2 (0.85) ABCG2AURKAMAOAMAPTNPC1
SCHEMBL4610666 0.80 ABCG2 (0.85) ABCG2AURKAMAOAMAPTNPC1
SCHEMBL4456573 0.80 ABCG2 (0.76) ABCG2MAOACHRNA7MAPTMEN1
SCHEMBL7098150 0.80 ABCG2 (0.62) ABCG2MAPT
SCHEMBL7100046 0.79 AR (0.72) ABCG2MAPTMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003097577-A1 CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME SYNTH'E163 (SOCIETE ANONYME) (FR) 2003-11-27 WO claimed
WO-2003097577-A1 CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME SYNTH'E163 (SOCIETE ANONYME) (FR) 2003-11-27 WO disclosed