Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.72 |
| ▸ | MAOB | P27338 | 4/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TFEB | P19484 | 1/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096835 | 0.89 | NFE2L2 (0.63) | ARMAOBNR1H4MAPTNPC1 | |
| SCHEMBL4535102 | 0.88 | AR (0.80) | ARMAOBNR1H4MAPTNPC1 | |
| SCHEMBL7098150 | 0.86 | ABCG2 (0.62) | ARMAOBNR1H4MAPTNFE2L2 | |
| SCHEMBL7097152 | 0.85 | ABCG2 (0.63) | ARMAOBNR1H4MAPTLMNA | |
| SCHEMBL7096821 | 0.85 | PDE4A (0.70) | MAOBMAPTLMNAKDM4EPOLB | |
| SCHEMBL7098090 | 0.85 | MAPT (0.71) | MAPTNPC1LMNARAB9AKDM4E | |
| SCHEMBL7096577 | 0.85 | AR (0.61) | ARMAOBNR1H4MAPTNPC1 | |
| SCHEMBL5084274 | 0.84 | AR (1.00) | ARMAOBNR1H4MAPTNPC1 | |
| SCHEMBL5084268 | 0.84 | AR (1.00) | ARMAOBNR1H4MAPTNPC1 | |
| SCHEMBL30807180 | 0.84 | AR (1.00) | ARMAOBNR1H4MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | claimed |
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | disclosed |