SCHEMBL710222

SCHEMBL710222

O=C(O)c1ccc(-c2ccc(-c3ccc(C(=O)O)c(C(=O)O)c3)cc2)cc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.60
KDM4E B2RXH2 1/20 0.60
GFER P55789 1/20 0.60
RXFP1 Q9HBX9 1/20 0.60
ACMSD Q8TDX5 4/20 0.59
MCL1 Q07820 4/20 0.59
HNF4A P41235 2/20 0.59
DHFR P00374 1/20 0.59
DCLRE1A Q6PJP8 1/20 0.52
DCLRE1B Q9H816 1/20 0.52
PPM1B O75688 1/20 0.52
CFD P00746 1/20 0.50
ALDH1A1 P00352 1/20 0.50
ALOX15 P16050 1/20 0.50
LCK P06239 1/20 0.50
CYP1A2 P05177 1/20 0.50
PTPN1 P18031 1/20 0.48
CDC25B P30305 2/20 0.48
HSD17B10 Q99714 2/20 0.48
CDC25A P30304 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29436303 1.00 KMT2A (0.60) KMT2AKDM4EGFERRXFP1ACMSD
SCHEMBL9550353 1.00 KMT2A (0.60) KMT2AKDM4EGFERRXFP1ACMSD
SCHEMBL30690397 0.97 KMT2A (0.62) KMT2AKDM4EGFERRXFP1ACMSD
SCHEMBL33365 0.97 KMT2A (0.62) KMT2AKDM4EGFERRXFP1ACMSD
SCHEMBL30690398 0.97 KMT2A (0.62) KMT2AKDM4EGFERRXFP1ACMSD
SCHEMBL277684 0.95 KMT2A (0.60) KMT2AKDM4EGFERRXFP1ACMSD
Methane SCHEMBL19809365 0.95 KMT2A (0.60) KMT2AKDM4EGFERRXFP1ACMSD
Water SCHEMBL4330613 0.95 KMT2A (0.60) KMT2AKDM4EGFERRXFP1ACMSD
SCHEMBL4449185 0.95 KMT2A (0.60) KMT2AKDM4EGFERRXFP1ACMSD
Hydrochloric Acid SCHEMBL17491114 0.95 KMT2A (0.60) KMT2AKDM4EGFERRXFP1ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 EP claimed
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US claimed
EP-2305632-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP claimed
US-20100272979-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2010-10-28 US claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 US claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
EP-1801097-A1 Photocrosslinkable materials Rolic AG (CH) 2007-06-27 EP claimed
EP-1799791-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2007-06-27 EP claimed
US-7034098-B2 POlyimide, polyamide; liquid crystals, opticsoptics ROLIC AG (CH) 2006-04-25 US claimed
WO-2006039824-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2006-04-20 WO claimed
EP-1368411-A1 PHOTOACTIVE POLYMER Rolic AG (CH) 2003-12-10 EP claimed
WO-2002062873-A9 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-10-03 WO claimed
WO-2002062873-A1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-08-15 WO claimed
EP-1229066-A1 Photoactive polymer Rolic AG (CH) 2002-08-07 EP claimed
EP-0758000-B1 Polyimide films from pyromellitic dianhydride and 2,2'-bis(perfluoroalkoxy)benzidines as alignment layers for liquid crystal displays DU PONT (US) 2001-12-19 EP claimed
US-5670609-A FILMS WITH LIQUID CCRYSTAL STRUCTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-23 US claimed
EP-0758000-A2 Polyimide films from pyromellitic dianhydride and 2,2'-bis(perfluoroalkoxy)benzidines as alignment layers for liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-12 EP claimed
EP-0260833-B1 PROCESS FOR PRODUCING POLYAMIDE ACID HAVING SILOXANE BONDS AND POLYIMIDE HAVING SILOXANE BONDS AND ISOINDOLOQUINAZOLINEDIONE RINGS HITACHI CHEMICAL COMPANY (JP) 1993-06-09 EP claimed
US-4912233-A Para- or meta-terphenyltetracarboxylic acid, dianhydride thereof and process for preparing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-03-27 US claimed
US-4847358-A HEAT RESISTANT ELECTRONICS HITACHI CHEMICAL COMPANY, LTD. (JP) 1989-07-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 KMT2A 558/4885KDM4E 844/4885GFER 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.