Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148893 | 0.98 | RELA (0.45) | RELAPPARACA1ALDH1A1TSHR | |
| SCHEMBL6827393 | 0.92 | CA1 (0.46) | RELAPPARACA1ALDH1A1TSHR | |
| SCHEMBL7101496 | 0.90 | RELA (0.54) | RELAPPARACA1ALDH1A1TSHR | |
| SCHEMBL7100793 | 0.89 | RELA (0.61) | RELAPPARACA1ALDH1A1TSHR | |
| SCHEMBL7103762 | 0.89 | RELA (0.61) | RELAPPARACA1ALDH1A1TSHR | |
| SCHEMBL31299681 | 0.89 | RELA (0.61) | RELAPPARACA1ALDH1A1TSHR | |
| SCHEMBL7689617 | 0.85 | RELA (0.61) | RELAPPARACA1CA2CA12 | |
| SCHEMBL14081786 | 0.85 | RELA (0.61) | RELAPPARACA1CA2CA12 | |
| SCHEMBL7103246 | 0.83 | RELA (0.39) | RELAALDH1A1TSHRCA2FAAH | |
| SCHEMBL9235692 | 0.83 | CA1 (0.50) | RELAPPARACA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-1020437-A1 | PROCESS FOR PRODUCING HALOGENOALKYLSULFONAMIDE DERIVATIVES | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |