Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830674 | 0.91 | RELA (0.33) | RELATSHRALDH1A1CA2TDP1 | |
| SCHEMBL7102343 | 0.83 | RELA (0.47) | RELATSHRALDH1A1CA2FAAH | |
| SCHEMBL7691856 | 0.82 | RELA (0.53) | RELACA2FAAH | |
| SCHEMBL19776014 | 0.82 | RELA (0.53) | RELACA2FAAH | |
| SCHEMBL11883426 | 0.82 | RELA (0.53) | RELACA2FAAH | |
| SCHEMBL7101496 | 0.82 | RELA (0.54) | RELATSHRALDH1A1CA2FAAH | |
| SCHEMBL9233467 | 0.81 | — | — | |
| SCHEMBL1148893 | 0.81 | RELA (0.45) | RELATSHRALDH1A1CA2TDP1 | |
| SCHEMBL7103762 | 0.80 | RELA (0.61) | RELATSHRALDH1A1CA2FAAH | |
| SCHEMBL31299681 | 0.80 | RELA (0.61) | RELATSHRALDH1A1CA2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-1020437-A1 | PROCESS FOR PRODUCING HALOGENOALKYLSULFONAMIDE DERIVATIVES | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |