Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101057 | 0.86 | MAPT (0.83) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL7101290 | 0.86 | MAPT (0.68) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL7096205 | 0.86 | PDE4A (0.67) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL7193687 | 0.82 | MAOB (0.74) | ALDH1A1MAPTABCG2APPMAOB | |
| SCHEMBL31234931 | 0.82 | MAOB (0.74) | ALDH1A1MAPTABCG2APPMAOB | |
| SCHEMBL7193689 | 0.82 | MAOB (0.74) | ALDH1A1MAPTABCG2APPMAOB | |
| SCHEMBL7097185 | 0.82 | ALDH1A1 (0.68) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL7097566 | 0.82 | ABCG2 (0.61) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL7099965 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL7098150 | 0.81 | ABCG2 (0.62) | MAPTABCG2APPNFE2L2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | claimed |
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | disclosed |