SCHEMBL7101057

SCHEMBL7101057

CNc1ccccc1C(=O)C=Cc1ccccc1OC

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.83
KDM4E B2RXH2 2/20 0.83
HPGD P15428 2/20 0.83
RECQL P46063 2/20 0.83
MEN1 O00255 1/20 0.83
ALDH1A1 P00352 1/20 0.83
POLB P06746 1/20 0.83
HTT P42858 1/20 0.83
KMT2A Q03164 1/20 0.83
AR P10275 4/20 0.68
MAOB P27338 3/20 0.68
NR1H4 Q96RI1 3/20 0.64
NPC1 O15118 2/20 0.61
LMNA P02545 2/20 0.61
BCHE P06276 1/20 0.61
RAB9A P51151 1/20 0.61
TRPA1 O75762 1/20 0.61
TRPM8 Q7Z2W7 1/20 0.61
NFE2L2 Q16236 2/20 0.60
CYP1A1 P04798 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7097185 0.90 ALDH1A1 (0.68) MAPTKDM4EHPGDRECQLMEN1
SCHEMBL7102369 0.86 KDM4E (0.64) MAPTKDM4EHPGDRECQLMEN1
SCHEMBL7099965 0.86 KDM4E (0.63) MAPTKDM4EHPGDRECQLMEN1
SCHEMBL7096205 0.86 PDE4A (0.67) MAPTKDM4EHPGDRECQLMEN1
SCHEMBL7101290 0.86 MAPT (0.68) MAPTKDM4EHPGDRECQLMEN1
SCHEMBL4535102 0.85 AR (0.80) MAPTKDM4EHPGDRECQLMEN1
SCHEMBL7097566 0.84 ABCG2 (0.61) MAPTKDM4EHPGDRECQLMEN1
SCHEMBL30807180 0.81 AR (1.00) MAPTKDM4EHPGDRECQLMEN1
SCHEMBL5084274 0.81 AR (1.00) MAPTKDM4EHPGDRECQLMEN1
SCHEMBL5084268 0.81 AR (1.00) MAPTKDM4EHPGDRECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003097577-A1 CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME SYNTH'E163 (SOCIETE ANONYME) (FR) 2003-11-27 WO claimed
WO-2003097577-A1 CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME SYNTH'E163 (SOCIETE ANONYME) (FR) 2003-11-27 WO disclosed