Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097566 | 0.90 | ABCG2 (0.61) | ALDH1A1KDM4EMEN1POLBMAPT | |
| SCHEMBL7101057 | 0.90 | MAPT (0.83) | ALDH1A1KDM4EMEN1POLBMAPT | |
| SCHEMBL1764951 | 0.87 | NFE2L2 (0.70) | ALDH1A1KDM4EMEN1POLBMAPT | |
| SCHEMBL4864045 | 0.85 | NFE2L2 (0.72) | ALDH1A1KDM4EMEN1POLBMAPT | |
| SCHEMBL7099965 | 0.84 | KDM4E (0.63) | ALDH1A1KDM4EMEN1POLBMAPT | |
| SCHEMBL5084423 | 0.83 | MAOB (0.80) | ALDH1A1MAPTLMNANFE2L2ALOX5 | |
| SCHEMBL5084427 | 0.83 | MAOB (0.80) | ALDH1A1MAPTLMNANFE2L2ALOX5 | |
| SCHEMBL7102369 | 0.82 | KDM4E (0.64) | ALDH1A1KDM4EMEN1POLBMAPT | |
| SCHEMBL7096835 | 0.82 | NFE2L2 (0.63) | ALDH1A1KDM4EMEN1POLBMAPT | |
| SCHEMBL27794060 | 0.80 | NFE2L2 (0.60) | ALDH1A1KDM4EMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | claimed |
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | disclosed |