SCHEMBL7102387

SCHEMBL7102387

CC1(C)[C@H](C=C(Cl)Cl)[C@H]1C(=O)Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
LMNA P02545 6/20 0.44
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
HTT P42858 4/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TSHR P16473 4/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.43
ATM Q13315 2/20 0.41
TDP1 Q9NUW8 3/20 0.38
ADRA2A P08913 1/20 0.38
CNR1 P21554 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
GAA P10253 1/20 0.34
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7102385 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL8409202 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL8407543 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL9021196 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL8409198 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL3885618 0.86 LMNA (0.42) HPGDLMNAKMT2AMEN1HTT
SCHEMBL3885619 0.86 LMNA (0.42) HPGDLMNAKMT2AMEN1HTT
SCHEMBL8409028 0.86 LMNA (0.55) HPGDLMNAKMT2AMEN1HTT
SCHEMBL3885617 0.86 LMNA (0.42) HPGDLMNAKMT2AMEN1HTT
SCHEMBL16606352 0.86 LMNA (0.42) HPGDLMNAKMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57158765-A None JP disclosed
CN-109071410-B Ester compound and use thereof 大日本除虫菊株式会社 2022-11-01 CN disclosed
CN-109195944-B Ester compound and use thereof 大日本除虫菊株式会社 2022-06-14 CN disclosed
EP-0960565-B1 Pyrethroid compound and composition containing the same for controlling pests SUMITOMO CHEMICAL CO (JP) 2003-03-05 EP disclosed
US-6423745-B1 CONTROLLING ARTHROPODS SUMITOMO CHEMICAL CO., LTD. (JP) 2002-07-23 US disclosed
EP-0959065-B1 Pyrethroid compound and composition for controlling pest containing the same SUMITOMO CHEMICAL CO (JP) 2002-04-03 EP disclosed
EP-0960565-A1 Pyrethroid compound and composition containing the same for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-01 EP disclosed
EP-0959065-A1 Pyrethroid compound and composition for controlling pest containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-24 EP disclosed
US-5925676-A INSECICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-20 US disclosed
US-5817880-A 2-FLUOROALKYL-4-HYDROXYCYCLOPENT-2-ENONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-06 US disclosed
WO-1982002321-A1 (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES FMC CORP (US) 1982-07-22 WO disclosed
US-4333950-A MITICIDES FMC CORPORATION (US) 1982-06-08 US disclosed
US-4329518-A INSECTICIDES, ACARICIDES, MITICIDES FMC CORPORATION (US) 1982-05-11 US disclosed
US-4304733-A Novel allethrolone derivatives ROUSSEL UCLAF (FR) 1981-12-08 US disclosed
US-4287208-A ESPECIALLY USEFUL AGAINST INSECTS AND ACARIDS BAYER AKTIENGESELLSCHAFT (DE) 1981-09-01 US disclosed
EP-0020685-A4 INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. FMC CORP (US) 1981-07-16 EP disclosed
US-4265906-A BROMOPHENOXYCYANOBENZYL CYCLOPROPANECARBOXYLATE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-05-05 US disclosed
EP-0020685-A1 INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. FMC CORP (US) 1981-01-07 EP disclosed
US-4214004-A MITICIDES FMC CORPORATION (US) 1980-07-22 US disclosed
WO-1980001163-A1 INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED(1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS FMC CORP (US) 1980-06-12 WO disclosed