SCHEMBL8409202

SCHEMBL8409202

CC1(C)[C@H](C=C(Cl)Cl)[C@@H]1C(=O)Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
LMNA P02545 6/20 0.44
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
HTT P42858 4/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TSHR P16473 4/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.43
ATM Q13315 2/20 0.41
TDP1 Q9NUW8 3/20 0.38
ADRA2A P08913 1/20 0.38
CNR1 P21554 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
GAA P10253 1/20 0.34
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7102387 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL7102385 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL8407543 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL9021196 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL8409198 1.00 HPGD (0.47) HPGDLMNAKMT2AMEN1HTT
SCHEMBL3885618 0.86 LMNA (0.42) HPGDLMNAKMT2AMEN1HTT
SCHEMBL3885619 0.86 LMNA (0.42) HPGDLMNAKMT2AMEN1HTT
SCHEMBL8409028 0.86 LMNA (0.55) HPGDLMNAKMT2AMEN1HTT
SCHEMBL3885617 0.86 LMNA (0.42) HPGDLMNAKMT2AMEN1HTT
SCHEMBL16606352 0.86 LMNA (0.42) HPGDLMNAKMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5925676-A INSECICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-20 US disclosed
EP-0829467-A1 Novel ester compounds, pesticidal compositions containing the same and intermediates for synthesis thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-03-18 EP disclosed
EP-0174739-B1 Process for obtaining an insecticidal product and composites thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-25 EP disclosed
US-4701464-A CONTROLLING LEAF-BEARING AND SOIL-BEARING INSECTS FMC CORPORATION (US) 1987-10-20 US disclosed
US-4694013-A Insecticidal and acaricidal phenoxypyrdinyl esters and intermediates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-15 US disclosed
EP-0223521-A2 Insecticidal and acaricidal phenoxypyridinyl esters and intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-27 EP disclosed
EP-0176594-A1 FLUOROPYRIDINYLMETHYL CYCLOPROPANECARBOXYLATE INSECTICIDES AND INTERMEDIATES FMC Corporation (US) 1986-04-09 EP disclosed
WO-1985004553-A1 FLUOROPYRIDINYLMETHYL CYCLOPROPANECARBOXYLATE INSECTICIDES AND INTERMEDIATES FMC CORPORATION (US) 1985-10-24 WO disclosed
US-4536591-A Insecticidal [1,1'-biphenyl]-3-ylmethyl esters FMC CORPORATION (US) 1985-08-20 US disclosed
EP-0067461-B1 PREPARATION OF CYANOBENZYL CYCLOPROPANE CARBOXYLATES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-07-17 EP disclosed
WO-1982002321-A1 (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES FMC CORP (US) 1982-07-22 WO disclosed
US-4329518-A INSECTICIDES, ACARICIDES, MITICIDES FMC CORPORATION (US) 1982-05-11 US disclosed
EP-0049977-A1 Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them FMC Corporation (US) 1982-04-21 EP disclosed
US-4322535-A REACTION OF AN ACYL HALIDE, ALDEHYDE, AND CYANIDE SALT USING A CATALYTIC AMPHOTERIC SURFACTANT OF AN AMINO ALKYLSULFONATE FMC CORPORATION (US) 1982-03-30 US disclosed
US-4308279-A STEREOISOMERS FMC CORPORATION (US) 1981-12-29 US disclosed
US-4299776-A AN A-CYANO-3-PHENOXYBENZYL ESTER FROM THE ACYL HALIDE, 3-PHENOXYBENZALDEHYDE AND A CYANIDE SALT FMC CORPORATION (US) 1981-11-10 US disclosed
US-4261921-A CYCLIC CRYSTALLIZATION OF STEREOISOMERS FROM RACEMIC MIXTURE FOLLOED BY RACEMIZATION OF MOTHER LIQUOR FMC CORPORATION (US) 1981-04-14 US disclosed
EP-0026542-A1 Preparation of esters containing an alpha cyano group in the alcohol portion of the ester FMC Corporation (US) 1981-04-08 EP disclosed
US-4254051-A ALPHA-CYANO ESTERS BY REACTING AN ACYL HALIDE WITH 3-PHENOXYBENZALDEHYDE AND A CYANIDE SALT FMC CORPORATION (US) 1981-03-03 US disclosed
EP-0022382-A1 Crystalline insecticidal pyrethroid enantiomer pair, process for preparation and composition FMC Corporation (US) 1981-01-14 EP disclosed