Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965716 | 0.79 | CCR5 (0.39) | ALDH1A1KMT2AKDM4EL3MBTL1CCR5 | |
| SCHEMBL25480523 | 0.78 | L3MBTL1 (0.35) | ALDH1A1KMT2AKDM4EL3MBTL1CCR5 | |
| SCHEMBL965813 | 0.78 | CCR5 (0.39) | ALDH1A1KMT2AKDM4EEPHX1L3MBTL1 | |
| SCHEMBL11044933 | 0.77 | DRD2 (0.47) | ALDH1A1ADRA2ASMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL11049209 | 0.77 | DRD2 (0.47) | ALDH1A1ADRA2ASMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL9547544 | 0.76 | EPHX2 (0.41) | ALDH1A1ADRA2ASMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL5987335 | 0.76 | EPHX2 (0.40) | ALDH1A1ADRA2ASMN1; SMN2EPHX2KDM4E | |
| SCHEMBL23135929 | 0.74 | CCR5 (0.44) | ALDH1A1KMT2AKDM4EEPHX1L3MBTL1 | |
| SCHEMBL969305 | 0.73 | L3MBTL1 (0.41) | ALDH1A1KMT2AKDM4EL3MBTL1CCR5 | |
| SCHEMBL7024470 | 0.72 | NPY5R (0.49) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042730-A1 | Substituted Arylketones | HERRMANN STEFAN | 2009-02-12 | — | — | US | disclosed |
| US-7456133-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-6531600-B1 | 8-substituted xanthines have a protective effect against the consequences of cerebral metabolic inhibition; cerebral vascular and neuronal degenerative disorders; 6-aminouracil intermediate is claimed | BEECHAM GROUP P.L.C. (GB) | 2003-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042730-A1 | Substituted Arylketones | CYP1A1, CYP1B1, CYP1A2 | ALDH1A1 37/4885ADRA2A 310/4885SMN1; SMN2 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.