Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.85 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.70 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.70 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.70 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.70 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.70 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.70 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820281 | 1.00 | ALDH1A1 (0.85) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8088391 | 1.00 | ALDH1A1 (0.85) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL5081086 | 1.00 | ALDH1A1 (0.85) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL3943933 | 1.00 | ALDH1A1 (0.85) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL2351099 | 0.98 | ALDH1A1 (0.89) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL1932191 | 0.92 | ALDH1A1 (1.00) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL4412163 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL4408377 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8364505 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL4280874 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5111392-A | — | — | None | — | — | JP | disclosed |
| CN-107021943-B | 7-epi-baccatin III derivatives, and preparation method and application thereof | 中国科学院上海药物研究所 | 2020-12-29 | — | — | CN | disclosed |
| US-8124778-B2 | Tricyclic inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124778-B2 | Tricyclic inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124778-B2 | Tricyclic inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100216750-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216750-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216750-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-08-26 | — | — | US | disclosed |
| EP-2161997-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Boger, Dale L. (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150492-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008150492-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-11 | — | — | WO | disclosed |
| US-7452960-B2 | Polyhydroxyalkanoate copolymer, resin composition, molded product, toner, image forming method and image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2008-11-18 | — | — | US | disclosed |
| US-20060040196-A1 | New polyhydroxyalkanoate copolymer, resin composition, molded product, toner, image forming method and image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2006-02-23 | — | — | US | disclosed |
| WO-2004041905-A1 | NEW POLYHYDROXYALKANOATE COPOLYMER, RESIN COMPOSITION, MOLDED PRODUCT, TONER, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2004-05-21 | — | — | WO | disclosed |
| JP-H05111392-A | PRODUCTION OF OPTICALLY ACTIVE SULFUR-CONTAINING COMPOUND | NIPPON SODA CO LTD | 1993-05-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216750-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FADS1, FAAH, SCD | ALDH1A1 753/4885HDAC1 129/4885HDAC2 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.