Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321698 | 0.98 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL5787834 | 0.96 | SMN1; SMN2 (0.42) | ALDH1A1LMNAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL373936 | 0.91 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL1152835 | 0.89 | SMN1; SMN2 (0.42) | ALDH1A1LMNAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL254353 | 0.87 | SMN1; SMN2 (0.41) | ALDH1A1LMNAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL9806689 | 0.87 | SMN1; SMN2 (0.41) | ALDH1A1LMNAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL713102 | 0.85 | SMN1; SMN2 (0.46) | ALDH1A1LMNAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL7369559 | 0.83 | SMN1; SMN2 (0.42) | ALDH1A1LMNAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL10850510 | 0.82 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9416724 | 0.82 | MEN1 (0.40) | ALDH1A1LMNAHSD17B10SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267539-A1 | HISTONE DEACETYLASE INHIBITORS | The University of Queensland (AU) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022133551-A1 | HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-06-30 | — | — | WO | disclosed |
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-05-14 | — | — | US | disclosed |
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-05-14 | — | — | US | disclosed |
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-05-14 | — | — | US | disclosed |
| EP-2852575-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | Actelion Pharmaceuticals Ltd. (CH) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013175397-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD (CH) | 2013-11-28 | — | — | WO | disclosed |
| EP-1090916-B1 | 4-methylene-1,3-dioxolanes having functional groups | DAINIPPON INK & CHEMICALS (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6388104-B1 | ODORLESS CROSSLINKING | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1090916-A1 | 4-methylene-1,3-dioxolanes having functional groups | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | IMPDH1, IMPDH2, ITPA | ALDH1A1 631/4885LMNA 4422/4885HSD17B10 3117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.