Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148741 | 0.91 | F2 (0.61) | F2NPSR1SPHK1CCR4ACE | |
| Hydrochloric Acid SCHEMBL7147488 | 0.90 | F2 (0.63) | F2NPSR1SPHK1CCR4ACE | |
| SCHEMBL7101554 | 0.87 | F2 (0.48) | F2NPSR1SPHK1CCR4ACE | |
| SCHEMBL7105056 | 0.85 | F2 (0.46) | F2F10HPNHGFACST14 | |
| SCHEMBL7102501 | 0.84 | F2 (0.49) | F2NPSR1SPHK1CCR4ACE | |
| SCHEMBL7107001 | 0.82 | CCR4 (0.49) | F2NPSR1SPHK1CCR4ACE | |
| SCHEMBL7107383 | 0.78 | F2 (0.55) | F2NPSR1SPHK1CCR4ACE | |
| Hydrochloric Acid SCHEMBL6920199 | 0.77 | ACE (0.46) | F2NPSR1CCR4ACE | |
| SCHEMBL7102567 | 0.77 | F2 (0.45) | F2F10HPNHGFACST14 | |
| SCHEMBL7104974 | 0.77 | ALDH1A1 (0.50) | F2NPSR1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |