Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107001 | 0.90 | CCR4 (0.49) | ACEF2DPP4DPP8DPP9 | |
| SCHEMBL11092917 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2ACEF2LTA4H | |
| Hydrochloric Acid SCHEMBL11098579 | 0.85 | ACE (0.46) | ALDH1A1SMN1; SMN2ACEF2 | |
| SCHEMBL7102501 | 0.82 | F2 (0.49) | ACEF2DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6920199 | 0.80 | ACE (0.46) | SMN1; SMN2ACEF2DPP4DPP8 | |
| SCHEMBL7378023 | 0.80 | HRH3 (0.49) | ALDH1A1SMN1; SMN2DPP4DPP8DPP9 | |
| SCHEMBL7148741 | 0.78 | F2 (0.61) | ACEF2NPSR1 | |
| SCHEMBL7101554 | 0.78 | F2 (0.48) | ACEF2DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL7147488 | 0.78 | F2 (0.63) | ACEF2NPSR1 | |
| SCHEMBL7102911 | 0.77 | F2 (0.53) | ACEF2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |