Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TMPRSS11D | O60235 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102569 | 0.92 | FKBP1A (0.46) | CYP3A4MAPTCYP2C9TSHRRAB9A | |
| SCHEMBL7106038 | 0.92 | TMPRSS11D (0.53) | CYP3A4CYP2C9TMPRSS11DF2F10 | |
| Hydrochloric Acid SCHEMBL27584411 | 0.91 | TMPRSS11D (0.52) | CYP3A4CYP2C9TMPRSS11DF2F10 | |
| Hydrochloric Acid SCHEMBL7140908 | 0.91 | TMPRSS11D (0.52) | CYP3A4CYP2C9TMPRSS11DF2F10 | |
| SCHEMBL7104147 | 0.87 | TMPRSS11D (0.48) | CYP3A4MAPTCYP2C9TSHRRAB9A | |
| SCHEMBL7104150 | 0.87 | TMPRSS11D (0.48) | CYP3A4MAPTCYP2C9TSHRRAB9A | |
| SCHEMBL7102494 | 0.86 | TMPRSS11D (0.58) | CYP3A4MAPTCYP2C9TSHRRAB9A | |
| SCHEMBL7105058 | 0.86 | TMPRSS11D (0.48) | CYP3A4CYP2C9TMPRSS11DF2F10 | |
| SCHEMBL7154250 | 0.85 | TMPRSS11D (0.47) | FKBP1ATMPRSS11DF2F10PLG | |
| SCHEMBL7363339 | 0.83 | TMPRSS11D (0.49) | CYP3A4CYP2C9TMPRSS11DF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |