Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 12/20 | 0.53 |
| ▸ | F2 | P00734 | 6/20 | 0.50 |
| ▸ | F10 | P00742 | 4/20 | 0.50 |
| ▸ | PLG | P00747 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27584411 | 0.99 | TMPRSS11D (0.52) | TMPRSS11DF2F10PLGCYP3A4 | |
| Hydrochloric Acid SCHEMBL7140908 | 0.99 | TMPRSS11D (0.52) | TMPRSS11DF2F10PLGCYP3A4 | |
| SCHEMBL7102504 | 0.92 | CYP3A4 (0.49) | TMPRSS11DF2F10PLGCYP3A4 | |
| SCHEMBL7105058 | 0.92 | TMPRSS11D (0.48) | TMPRSS11DF2F10PLGCYP3A4 | |
| SCHEMBL7363339 | 0.90 | TMPRSS11D (0.49) | TMPRSS11DF2F10PLGCYP3A4 | |
| Hydrochloric Acid SCHEMBL7156980 | 0.89 | TMPRSS11D (0.49) | TMPRSS11DF2F10PLGCYP3A4 | |
| SCHEMBL27470814 | 0.87 | ALDH1A1 (0.48) | TMPRSS11DF2F10PLGCYP3A4 | |
| SCHEMBL7107389 | 0.87 | ALDH1A1 (0.48) | TMPRSS11DF2F10PLGCYP3A4 | |
| SCHEMBL7102489 | 0.86 | TMPRSS11D (0.56) | TMPRSS11DF2F10PLGCYP3A4 | |
| SCHEMBL7102493 | 0.86 | TMPRSS11D (0.56) | TMPRSS11DF2F10PLGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361212-A1 | Peptide derivatives as antithrombotic agents | AstraZeneca AB (SE) | 2003-11-12 | — | — | EP | claimed |
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |
| EP-0672658-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | claimed |