Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 12/20 | 0.48 |
| ▸ | F2 | P00734 | 9/20 | 0.46 |
| ▸ | F10 | P00742 | 5/20 | 0.46 |
| ▸ | PLG | P00747 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102569 | 0.92 | FKBP1A (0.46) | TMPRSS11DF2F10PRSS1PRSS2 | |
| SCHEMBL7106038 | 0.92 | TMPRSS11D (0.53) | TMPRSS11DF2F10PLGPRSS1 | |
| Hydrochloric Acid SCHEMBL27584411 | 0.91 | TMPRSS11D (0.52) | TMPRSS11DF2F10PLGPRSS1 | |
| Hydrochloric Acid SCHEMBL7140908 | 0.91 | TMPRSS11D (0.52) | TMPRSS11DF2F10PLGPRSS1 | |
| SCHEMBL7363339 | 0.90 | TMPRSS11D (0.49) | TMPRSS11DF2F10PLGPRSS1 | |
| Hydrochloric Acid SCHEMBL7156980 | 0.89 | TMPRSS11D (0.49) | TMPRSS11DF2F10PLGPRSS1 | |
| SCHEMBL7102916 | 0.86 | F2 (0.52) | F2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL7102504 | 0.86 | CYP3A4 (0.49) | TMPRSS11DF2F10PLGCYP3A4 | |
| SCHEMBL7363788 | 0.86 | TMPRSS11D (0.45) | TMPRSS11DF2F10PLGPRSS1 | |
| SCHEMBL7102587 | 0.85 | TMPRSS11D (0.50) | TMPRSS11DF2F10PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |