Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095821 | 0.82 | KMT2A (1.00) | KMT2APKMSLC6A9MAPTGAA | |
| SCHEMBL7100913 | 0.77 | KMT2A (0.58) | KMT2APKMSLC6A9MAPTGAA | |
| SCHEMBL1219825 | 0.72 | KMT2A (0.74) | KMT2APKMSLC6A9MAPTGAA | |
| SCHEMBL7102535 | 0.70 | ALDH1A1 (0.68) | KMT2APKMSLC6A9MAPTGAA | |
| SCHEMBL14592445 | 0.68 | MAPT (0.66) | KMT2APKMSLC6A9MAPTGAA | |
| SCHEMBL11412778 | 0.67 | PDK2 (0.44) | MAPTGAARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2947342 | 0.66 | CA1 (0.41) | KMT2AMAPTGAAALDH1A1PDK2 | |
| SCHEMBL347140 | 0.65 | PDK2 (0.40) | KMT2AMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11017672 | 0.65 | GABRA1 (0.52) | KMT2AMAPTSMN1; SMN2ALDH1A1PDK2 | |
| SCHEMBL11696953 | 0.65 | MAPT (1.00) | KMT2APKMSLC6A9MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764886-B1 | Electrophotosensitive material containing a naphthoquinone derivative | KYOCERA MITA CORP (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-5994012-A | CHARGE GENERATING COMPOUND, CHARGE TRANSFER COMPOUND AND BINDER | MITA INDUSTRIAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5863688-A | REACTING 1,3-INDANDIONE DERIVATIVE WITH A BROMOACETIC ESTER TO FORM 1,3-INDANDIONE ESTER, ISOMERIZING THE ESTER DERIVATIVE IN PRESENCE OF SODIUM HYDRIDE TO FORM NAPHTHOIC ESTER, OXIDIZING TO FORM NAPHTHOQUINONE DERIVATIVE | MITA INDUSTRIAL CO., LTD (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0764886-A2 | Naphthoquinone derivative and electrophotosensitive material using the same | MITA INDUSTRIAL CO. LTD. (JP) | 1997-03-26 | — | — | EP | disclosed |