Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31132214 | 1.00 | LMNA (0.40) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL93485 | 0.91 | NPC1 (0.47) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL29358846 | 0.91 | NPC1 (0.47) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL1733769 | 0.90 | MAPK1 (0.35) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL8823408 | 0.89 | LMNA (0.43) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL23121469 | 0.85 | NPC1 (0.44) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL29382102 | 0.85 | NPC1 (0.45) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL373620 | 0.85 | NPC1 (0.45) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL21836053 | 0.85 | LMNA (0.41) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL25412291 | 0.84 | LMNA (0.44) | LMNANPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811393-B1 | SOFT INTRAOCULAR LENS | HOYA CORP (JP) | 2002-01-23 | — | — | EP | claimed |
| EP-0811393-A1 | SOFT INTRAOCULAR LENS | HOYA CORPORATION (JP) | 1997-12-10 | — | — | EP | claimed |
| US-11634558-B2 | Optical resin material for chromatic aberration correction | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-04-25 | — | — | US | disclosed |
| US-20210292447-A1 | POLYMER MATERIAL AND INTRAOCULAR LENS | SHANGHAI FULO MEDICAL INSTRUMENT CO., LTD. (CN) | 2021-09-23 | — | — | US | disclosed |
| EP-3805290-A1 | POLYMER MATERIAL AND INTRAOCULAR LENS | Shanghai Chartwell Medical Instrument Co., Ltd (CN) | 2021-04-14 | — | — | EP | disclosed |
| US-20200270421-A1 | OPTICAL RESIN MATERIAL FOR CHROMATIC ABERRATION CORRECTION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-08-27 | — | — | US | disclosed |
| US-9529119-B2 | Method for fabricating silicone-containing copolymer molded article having hydrophilic surface and silicone-hydrogel contact lens having hydrophilic surface | HOYA CORPORATION (JP) | 2016-12-27 | — | — | US | disclosed |
| EP-2845708-B1 | METHOD FOR PRODUCING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE, AND SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORP (JP) | 2016-07-06 | — | — | EP | disclosed |
| EP-2926967-A1 | Silicone hydrogel contact lens having hydrophilic surface | HOYA CORPORATION (JP) | 2015-10-07 | — | — | EP | disclosed |
| EP-2845708-A1 | METHOD FOR PRODUCING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE, AND SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| EP-0823643-B1 | Soft contact lens with high moisture content and method for producing the same | HOYA CORP (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0811393-B1 | SOFT INTRAOCULAR LENS | HOYA CORP (JP) | 2002-01-23 | — | — | EP | disclosed |
| US-5965630-A | POLYMERIZING HYDROPHILIC MONOMERS, HYDROXYETHYL METHACRYLATE, VINYL-2-PYRROLIDONE, DIMETHYLACRYLAMIDE, AN ALKYL METHACRYLATE AND A CROSSLINKER IN A DILUENT OF TRIETHYLENE GLYCOL, DI- OR TRIETHYLENE GLYCOL MONOMETHYL ETHER | HOYA CORPORATION (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0823643-A1 | Soft contact lens with high moisture content and method for producing the same | HOYA CORPORATION (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0811393-A1 | SOFT INTRAOCULAR LENS | HOYA CORPORATION (JP) | 1997-12-10 | — | — | EP | disclosed |