Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | PDE4A | P27815 | 6/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490426 | 0.92 | KMT2A (0.75) | KMT2ANR1I2AHRLMNAPKM | |
| SCHEMBL14869526 | 0.89 | CYP1A2 (0.53) | KMT2ANR1I2AHRLMNAPDE4A | |
| SCHEMBL9102166 | 0.89 | CYP1A2 (0.53) | KMT2ANR1I2AHRLMNAPDE4A | |
| SCHEMBL13784076 | 0.89 | KMT2A (0.63) | KMT2ANR1I2AHRLMNAPDE4A | |
| SCHEMBL7099893 | 0.87 | KMT2A (0.69) | KMT2ANR1I2AHRLMNAPKM | |
| SCHEMBL2356311 | 0.86 | LMNA (0.79) | KMT2ANR1I2AHRLMNAPDE4A | |
| SCHEMBL15401992 | 0.85 | KMT2A (0.73) | KMT2ANR1I2AHRLMNAPDE4A | |
| Diethylamine SCHEMBL10892424 | 0.84 | KMT2A (0.66) | KMT2ANR1I2AHRLMNAPDE4A | |
| SCHEMBL7101507 | 0.83 | LMNA (0.83) | KMT2ALMNAPDE4ACYP1A2CYP2C19 | |
| SCHEMBL29609639 | 0.83 | LMNA (0.83) | KMT2ALMNAPDE4ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751170-B1 | Silicone derivatives, their production and use | CHIBA FLOUR MILLING (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-5859243-A | AMINOSILICONES HAVING PYRIMIDINYL GROUPS BOUND TO THE AMINO GROUPS; USED TO GEL SILICONE OIL OR TO INCREASE THE VISCOSITY STABLY AND HOMOGENEOUSLY; BASES FOR COSMETICS, DRUGS, INDUSTRIAL MATERIAL; FEEL; TEXTURE | CHIBA FLOUR MILLING CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| US-5712391-A | POLYSILOXANES MODIFIED WITH TRIAZINE GROUPS AND DIAMINE COMPOUNDS FOR COSMETICS | CHIBA FLOUR MILLING CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0751170-A2 | Silicone derivatives, their production and use | Chiba Flour Milling Co., Ltd. (JP) | 1997-01-02 | — | — | EP | disclosed |