SCHEMBL15401992

SCHEMBL15401992

CCCCCCNc1nc(Cl)nc(NC)n1

nearest known ligand 0.73

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.73
LMNA P02545 1/20 0.50
KCNH3 Q9ULD8 2/20 0.47
PDE4A P27815 5/20 0.47
NR1I2 O75469 1/20 0.45
AHR P35869 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
DNM2 P50570 3/20 0.44
PKM P14618 1/20 0.41
RAD52 P43351 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13784076 0.93 KMT2A (0.63) KMT2ALMNAKCNH3PDE4ANR1I2
SCHEMBL7862893 0.93 KMT2A (0.83) KMT2ALMNAKCNH3NR1I2AHR
SCHEMBL11787843 0.93 KMT2A (0.83) KMT2ALMNAKCNH3NR1I2AHR
SCHEMBL20694824 0.91 KMT2A (0.81) KMT2ALMNAKCNH3NR1I2AHR
SCHEMBL7100653 0.91 KMT2A (0.80) KMT2ALMNAKCNH3NR1I2AHR
SCHEMBL20680484 0.89 KMT2A (0.78) KMT2ALMNAKCNH3NR1I2AHR
SCHEMBL17563553 0.89 KMT2A (0.77) KMT2ALMNAKCNH3NR1I2AHR
SCHEMBL10912439 0.89 KMT2A (0.77) KMT2ALMNAKCNH3NR1I2AHR
SCHEMBL7937257 0.89 KMT2A (0.77) KMT2ALMNAKCNH3NR1I2AHR
SCHEMBL1562316 0.89 KMT2A (0.77) KMT2ALMNAKCNH3NR1I2AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4112607-A1 AMINO LIPID COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Shenzhen Shenxin Biotechnology Co., Ltd. (CN) 2023-01-04 EP disclosed
US-9346768-B2 Molecular glasses with functionalizable groups HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENSE (CA) 2016-05-24 US disclosed
US-9328076-B2 Molecular glasses with functionalizable groups HER MAJESTY IN THE RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF DEFENSE (CA) 2016-05-03 US disclosed
US-20150232433-A1 Molecular Glasses With Functionalizable Groups HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) 2015-08-20 US disclosed
US-20140005370-A1 MOLECULAR GLASSES WITH FUNCTIONALIZABLE GROUPS HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) 2014-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140005370-A1 MOLECULAR GLASSES WITH FUNCTIONALIZABLE GROUPS GNG2, GDI1, F12 KMT2A 3635/4885LMNA 3537/4885KCNH3 172/4885
US-20150232433-A1 Molecular Glasses With Functionalizable Groups GDI1, GNG2, F12 KMT2A 3732/4885LMNA 3433/4885KCNH3 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.