SCHEMBL7102927

SCHEMBL7102927

Cc1ccc(S(=O)(=O)N(C(N)=O)c2ccc(Oc3ccc(N(C(N)=O)S(=O)(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 6/20 0.59
LMNA P02545 4/20 0.59
MAPT P10636 5/20 0.54
KDM4E B2RXH2 2/20 0.54
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
GAA P10253 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
HSP90AA1 P07900 1/20 0.51
THRB P10828 1/20 0.50
NR3C1 P04150 1/20 0.50
PTGES O14684 1/20 0.49
ALOX5 P09917 1/20 0.49
ALDH1A1 P00352 3/20 0.48
POLB P06746 1/20 0.48
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6244082 0.92 TP53 (0.55) TP53LMNAMAPTKDM4ECYP1A2
SCHEMBL27991408 0.91 LMNA (0.62) TP53LMNAMAPTKDM4ECYP1A2
SCHEMBL6243993 0.91 LMNA (0.62) TP53LMNAMAPTKDM4ECYP1A2
SCHEMBL6243492 0.90 TP53 (0.53) TP53LMNAMAPTKDM4ECYP1A2
SCHEMBL9478142 0.90 TP53 (0.73) TP53LMNAMAPTKDM4ECYP1A2
SCHEMBL22187541 0.87 PPARG (0.62) TP53LMNAMAPTKDM4ECYP1A2
SCHEMBL6239393 0.87 LMNA (0.62) TP53LMNAMAPTKDM4ECYP1A2
SCHEMBL6244985 0.86 LMNA (0.57) TP53LMNAMAPTKDM4ECYP1A2
SCHEMBL6881654 0.86 TP53 (0.54) TP53LMNAMAPTKDM4ECYP1A2
SCHEMBL7999295 0.84 LMNA (0.76) TP53LMNAMAPTKDM4ETHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0949087-B1 Heat-fixable thermosensitive recording material OJI PAPER CO (JP) 2003-09-17 EP disclosed
US-6335306-B1 SUBBING LAYER OF COLOR DEVELOPABILITY REDUCING AGENT AND IMAGE-FORMING LAYER OF COLORLESS OR LIGHT-COLORED DYE PRECURSOR AND COLOR-DEVELOPER; HEATED AND FIXED AT HIGH TEMPERATURE, IMAGE HAS HIGH SOLVENT RESISTANCE, IMAGE CLARITY OJI PAPER CO., LTD. (JP) 2002-01-01 US disclosed
EP-0949087-A1 Heat-fixable thermosensitive recording material OJI PAPER CO., LTD. (JP) 1999-10-13 EP disclosed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP disclosed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US disclosed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP disclosed