Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102927 | 0.90 | TP53 (0.59) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL27991408 | 0.89 | LMNA (0.62) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL6243993 | 0.89 | LMNA (0.62) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL22187541 | 0.86 | PPARG (0.62) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL6239393 | 0.86 | LMNA (0.62) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL8620628 | 0.86 | TP53 (0.55) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL6244985 | 0.85 | LMNA (0.57) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL6881654 | 0.85 | TP53 (0.54) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL834715 | 0.84 | TP53 (1.00) | TP53LMNAMAPTTHRBALDH1A1 | |
| SCHEMBL6465065 | 0.83 | TP53 (0.54) | TP53LMNAMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5116459-A | — | — | None | — | — | JP | disclosed |
| JP-H05116459-A | THERMAL RECORDING BODY | OJI PAPER CO LTD | 1993-05-14 | — | — | JP | disclosed |