SCHEMBL6239393

SCHEMBL6239393

Cc1ccc(S(=O)(=O)N(C(N)=O)c2ccc(OCCOc3ccc(N(C(N)=O)S(=O)(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.62
TP53 P04637 6/20 0.60
MAPT P10636 6/20 0.60
THRB P10828 1/20 0.56
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
GAA P10253 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
ALDH1A1 P00352 1/20 0.51
POLB P06746 1/20 0.51
KDM4E B2RXH2 2/20 0.50
HSP90AA1 P07900 1/20 0.48
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7102927 0.87 TP53 (0.59) LMNATP53MAPTTHRBCYP1A2
SCHEMBL27991408 0.87 LMNA (0.62) LMNATP53MAPTTHRBCYP1A2
SCHEMBL6243993 0.87 LMNA (0.62) LMNATP53MAPTTHRBCYP1A2
SCHEMBL9478142 0.86 TP53 (0.73) LMNATP53MAPTTHRBCYP1A2
SCHEMBL22187541 0.84 PPARG (0.62) LMNATP53MAPTTHRBCYP1A2
SCHEMBL6244985 0.83 LMNA (0.57) LMNATP53MAPTCYP1A2CYP3A4
SCHEMBL6881654 0.83 TP53 (0.54) LMNATP53MAPTTHRBCYP1A2
SCHEMBL27679 0.82 LMNA (0.54) LMNATP53MAPTTHRBCYP1A2
SCHEMBL6244082 0.81 TP53 (0.55) LMNATP53MAPTCYP1A2CYP3A4
SCHEMBL7999295 0.80 LMNA (0.76) LMNATP53MAPTTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535887-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
US-5256618-A Using a sulfonylurea or -thiourea-type developer and leuco dye. resistance to oil and fats, e.g, plasticizer, moisture and heat; colorfastness; storage stability; thermography OJI PAPER CO., LTD. (JP) 1993-10-26 US claimed
EP-0535887-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP claimed
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
EP-1314574-B1 Method of fixing a thermosensitive recording material OJI PAPER CO (JP) 2005-07-06 EP disclosed
EP-0949087-B1 Heat-fixable thermosensitive recording material OJI PAPER CO (JP) 2003-09-17 EP disclosed
EP-1314574-A1 Thermosensitive recording material of heat fixing type and method of fixing the same OJI PAPER CO., LTD. (JP) 2003-05-28 EP disclosed
US-6335306-B1 SUBBING LAYER OF COLOR DEVELOPABILITY REDUCING AGENT AND IMAGE-FORMING LAYER OF COLORLESS OR LIGHT-COLORED DYE PRECURSOR AND COLOR-DEVELOPER; HEATED AND FIXED AT HIGH TEMPERATURE, IMAGE HAS HIGH SOLVENT RESISTANCE, IMAGE CLARITY OJI PAPER CO., LTD. (JP) 2002-01-01 US disclosed
EP-0949087-A1 Heat-fixable thermosensitive recording material OJI PAPER CO., LTD. (JP) 1999-10-13 EP disclosed