Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ACP3 | P15309 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20483656 | 0.79 | ALDH1A1 (0.36) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL8019682 | 0.69 | ACP3 (0.39) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL2700992 | 0.69 | ALDH1A1 (0.40) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL20483733 | 0.69 | ACP3 (0.36) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL27511411 | 0.68 | ALDH1A1 (0.50) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL5010143 | 0.67 | KIF11 (0.41) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL1538715 | 0.66 | ALDH1A1 (0.48) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL5010732 | 0.66 | ACP3 (0.42) | HSD17B10TDP1ACP3CYP1A2HPGD | |
| SCHEMBL1538546 | 0.65 | CYP2A6 (0.54) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL1161290 | 0.65 | KDM4E (0.53) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922708-B1 | Production method of borate compounds | SHOWA DENKO KK (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6002044-A | REACTING A LITHIUM OR MAGNEISIUM, A HALIDE AND A BORONATE PRECURSOR OBTAINED IN A FIRSST SIMILAR STEP USING A BORIDE; ADDING AN ONIIUM HALIDE TO THE METAL BORATE; PURITY | SHOWA DENKO K.K. (JP) | 1999-12-14 | — | — | US | disclosed |
| EP-0922708-A2 | Production method of borate compounds | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1999-06-16 | — | — | EP | disclosed |