Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TERT | O14746 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558340 | 0.97 | MAPT (0.72) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL950959 | 0.88 | MAPT (0.72) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL24288764 | 0.86 | ALDH2 (0.65) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL27769243 | 0.85 | ALDH1A1 (0.68) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL16335646 | 0.84 | ALDH1A1 (0.69) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL3419148 | 0.83 | ALDH2 (0.74) | XDHALDH2MAOAMAOB | |
| SCHEMBL29482681 | 0.81 | RAB9A (1.00) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL571161 | 0.81 | RAB9A (1.00) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11560028 | 0.81 | MAPT (0.77) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL1421774 | 0.80 | ABCG2 (0.61) | MAPTNPC1RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097004-A1 | WHITENING COMPOSITIONS COMPRISING MELANIN BIOSYNTHESIS INHIBITING COMPOUNDS | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2003-11-27 | — | — | WO | disclosed |