SCHEMBL7103027

SCHEMBL7103027

CCCc1nc(SC)c(OC(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCC2CC2)cc1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 17/20 0.76
AGTR1 P30556 10/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7101649 0.92 AGTR2 (0.71) AGTR2AGTR1
SCHEMBL7021275 0.90 AGTR2 (0.79) AGTR2AGTR1
SCHEMBL6544948 0.90 AGTR2 (0.79) AGTR2AGTR1
SCHEMBL7103025 0.89 AGTR1 (0.94) AGTR2AGTR1
SCHEMBL7026926 0.88 AGTR2 (0.66) AGTR2AGTR1
SCHEMBL7026217 0.86 AGTR2 (0.63) AGTR2AGTR1
SCHEMBL8351241 0.86 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL7701060 0.86 AGTR2 (0.80) AGTR2AGTR1
SCHEMBL9565544 0.85 AGTR2 (0.61) AGTR2AGTR1
SCHEMBL7022995 0.85 AGTR2 (0.70) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0560177-B1 Imidazole derivatives having biphenylsulphonylurea or biphenylsulfonylurethane side chains, process for their production and use thereof HOECHST AG (DE) 2003-01-08 EP disclosed
EP-0560177-A1 Imidazole derivatives having biphenylsulphonylurea or biphenylsulfonylurethane side chains, process for their production and use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-15 EP disclosed