Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP3A5 | P20815 | 5/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093686 | 0.90 | MEN1 (0.62) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9251253 | 0.88 | MEN1 (0.72) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11193886 | 0.84 | CYP2D6 (0.56) | MEN1KMT2AP4HBOPRD1CYP2D6 | |
| SCHEMBL1138320 | 0.84 | MEN1 (0.79) | MEN1KMT2AOPRD1OPRM1OPRK1 | |
| SCHEMBL16225886 | 0.84 | MEN1 (0.79) | MEN1KMT2AOPRD1OPRM1OPRK1 | |
| SCHEMBL1138318 | 0.84 | MEN1 (0.79) | MEN1KMT2AOPRD1OPRM1OPRK1 | |
| SCHEMBL336219 | 0.83 | CYP2D6 (0.67) | MEN1KMT2AP4HBOPRD1OPRM1 | |
| SCHEMBL31023820 | 0.83 | OPRD1 (0.52) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16226307 | 0.78 | OPRD1 (0.63) | MEN1KMT2AOPRD1OPRM1OPRK1 | |
| Nitric Acid SCHEMBL11199010 | 0.78 | CYP3A4 (0.60) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |