SCHEMBL336219

SCHEMBL336219

Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.67
CYP19A1 P11511 1/20 0.67
MEN1 O00255 1/20 0.66
KMT2A Q03164 1/20 0.66
OPRD1 P41143 9/20 0.56
ACHE P22303 3/20 0.54
P4HB P07237 1/20 0.51
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
SIGMAR1 Q99720 1/20 0.49
OPRM1 P35372 1/20 0.49
OPRK1 P41145 1/20 0.49
OPRL1 P41146 1/20 0.49
KCNH2 Q12809 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16225886 0.93 MEN1 (0.79) CYP2D6CYP19A1MEN1KMT2AOPRD1
SCHEMBL1138318 0.93 MEN1 (0.79) CYP2D6CYP19A1MEN1KMT2AOPRD1
SCHEMBL1138320 0.93 MEN1 (0.79) CYP2D6CYP19A1MEN1KMT2AOPRD1
SCHEMBL7427630 0.93 CYP2D6 (0.59) CYP2D6CYP19A1MEN1KMT2AOPRD1
SCHEMBL8182035 0.91 CYP2D6 (0.57) CYP2D6CYP19A1MEN1KMT2AOPRD1
SCHEMBL11193886 0.90 CYP2D6 (0.56) CYP2D6CYP19A1MEN1KMT2AOPRD1
SCHEMBL16226147 0.88 MEN1 (0.67) CYP2D6CYP19A1MEN1KMT2AOPRD1
Acetic Acid SCHEMBL27992925 0.88 OPRD1 (0.65) CYP2D6CYP19A1MEN1KMT2AOPRD1
SCHEMBL16226307 0.87 OPRD1 (0.63) CYP2D6CYP19A1MEN1KMT2AOPRD1
Acetic Acid SCHEMBL27992880 0.87 OPRD1 (0.63) CYP2D6CYP19A1MEN1KMT2AOPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 652 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120117949-A Method for directly preparing tertiary amine compound from aromatic aldehyde, ketone and secondary amine 湖南大学 2025-06-10 CN claimed
CN-117447690-A Waterproof locking agent for oil field and synthesis method thereof 胜利油田物华化工厂 2024-01-26 CN claimed
CN-110967421-B Method for detecting related substances of flunarizine hydrochloride preparation 正大青春宝药业有限公司 2022-04-12 CN claimed
CN-110967421-A Method for detecting related substances of flunarizine hydrochloride preparation 正大青春宝药业有限公司 2020-04-07 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
US-8835492-B2 Temperature and pH sensitive block copolymer and polymeric hydrogels using the same SUNGYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2014-09-16 US claimed
US-20100233264-A1 TEMPERATURE AND pH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFTY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2010-09-16 US claimed
WO-2009031861-A2 TEMPERATURE AND PH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFETY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2009-03-12 WO claimed
WO-2008155777-A2 PROCESS FOR PREPARING EFLETRIZINE CADILA HEALTHCARE LIMITED (IN) 2008-12-24 WO claimed
US-20080293827-A1 Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR COROPORATE COLLABORATION (KR) 2008-11-27 US claimed
EP-0266549-B1 CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1991-06-19 EP claimed
EP-0266549-A1 Cinnamyl amines, process for their preparation and pharmaceutical compositions containing them BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1988-05-11 EP claimed
EP-0152799-B1 COMPOUNDS HAVING PERIPHERAL CALCIUM ANTAGONIST, ANTICONVULSIVE AND EUMETABOLIC ACTIVITY, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PULITZER ITALIANA S.p.A. (IT) 1987-10-28 EP claimed
EP-0152799-A1 Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them PULITZER ITALIANA S.p.A. (IT) 1985-08-28 EP claimed
CN-122059950-A Compounds with proteasome agonistic activity, preparation method and application thereof 浙大城市学院 2026-05-19 CN disclosed
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery UNIV JOHNS HOPKINS (US) 2026-04-02 US disclosed
US-4377578-A ANTIANAPHYLACTIC AGENTS, ANTIHISTAMINES JANSSEN PHARMACEUTICA, N.V. (BE) 1983-03-22 US disclosed
US-4250176-A BENZIMIDAZOLE-2-ONE, BENZOTHIAZOL-2-ONE, OR BENZOXAZOL-2-ONE SUBSTITUTIONS, ANTIANAPHALACTIC AGENTS, ANTIHISTAMINES JANSSEN PHARMACEUTICA N.V. (BE) 1981-02-10 US disclosed
US-4200641-A ANTIANAPHYLACTIC AGENTS, ANTIHISTAMINES JANSSEN PHARMACEUTICA, N.V. (BE) 1980-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233264-A1 TEMPERATURE AND pH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFTY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF CD44, PSAT1, ALAD CYP2D6 2707/4885CYP19A1 2439/4885MEN1 4843/4885
US-20080293827-A1 Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same LRBA, DAO, PAM CYP2D6 2139/4885CYP19A1 3270/4885MEN1 2599/4885
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery SLC43A1, SLC7A5, SLC7A1 CYP2D6 3859/4885CYP19A1 4306/4885MEN1 3141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.