Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.60 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093686 | 0.95 | MEN1 (0.62) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7103066 | 0.88 | MEN1 (0.55) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5549076 | 0.85 | MEN1 (0.79) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| SCHEMBL31023820 | 0.85 | OPRD1 (0.52) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL31023651 | 0.85 | CYP3A4 (0.57) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL219432 | 0.85 | MEN1 (1.00) | MEN1KMT2AOPRD1OPRM1KCNH2 | |
| SCHEMBL2794662 | 0.85 | MEN1 (1.00) | MEN1KMT2AOPRD1OPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL7006476 | 0.83 | MEN1 (0.96) | MEN1KMT2AOPRD1OPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL11456225 | 0.83 | MEN1 (0.96) | MEN1KMT2AOPRD1OPRM1KCNH2 | |
| Piperazine SCHEMBL28229145 | 0.83 | MEN1 (0.96) | MEN1KMT2AOPRD1OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |