SCHEMBL7103147

SCHEMBL7103147

Fc1c(Br)cccc1OCC1CC1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.44
HTR2C P28335 4/20 0.40
HTR2A P28223 2/20 0.40
HTR2B P41595 2/20 0.40
MCHR1 Q99705 3/20 0.39
KCNN4 O15554 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18706829 0.92 MCHR1 (0.48) HTR2CMCHR1
SCHEMBL2226051 0.89 DHFR (0.48) RIPK1HTR2CHTR2AHTR2BMCHR1
SCHEMBL15969381 0.82 RIPK1 (0.46) RIPK1HTR2CHTR2AHTR2BMCHR1
SCHEMBL5133567 0.82 RIPK1 (0.46) RIPK1HTR2CHTR2AHTR2BMCHR1
SCHEMBL981768 0.82 RIPK1 (0.53) RIPK1HTR2C
SCHEMBL29650225 0.80 ALDH1A1 (0.54) HTR2AHTR2B
SCHEMBL19692955 0.80 ALDH1A1 (0.54) HTR2AHTR2B
SCHEMBL19692956 0.80 ALDH1A1 (0.54) HTR2AHTR2B
SCHEMBL24153922 0.79 RIPK1 (0.47) RIPK1HTR2CHTR2AHTR2BMCHR1
SCHEMBL26770363 0.79 HTR2C (0.47) RIPK1HTR2CHTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003095441-A1 INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME PFIZER INC. (US) 2003-11-20 WO disclosed