Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099955 | 0.96 | MAPT (0.35) | MAPTKMT2ALMNANPC1ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7098580 | 0.94 | ACHE (0.37) | MAPTKMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL7531533 | 0.83 | MAPT (0.37) | MAPTKMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL8909050 | 0.80 | MAPT (0.39) | MAPTKMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL8046796 | 0.80 | KMT2A (0.44) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL7538206 | 0.80 | NPC1 (0.37) | MAPTKMT2ANPC1TP53CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL4197431 | 0.80 | LMNA (0.36) | MAPTKMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL7103169 | 0.79 | KMT2A (0.40) | MAPTKMT2ALMNANPC1ALDH1A1 | |
| Bromide SCHEMBL7103303 | 0.79 | KMT2A (0.43) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL13979971 | 0.79 | LMNA (0.43) | MAPTKMT2ALMNANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988551-B1 | CHEMILUMINESCENT ENERGY TRANSFER CONJUGATES AND THEIR USES AS LABELS IN BINDING ASSAYS | BAYER AG (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6165800-A | Chemiluminescent energy transfer conjugates and their uses as labels in binding assays | BAYER CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |