Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101655 | 1.00 | RIPK1 (0.38) | RIPK1HDAC4JAK2NTRK1TLR7 | |
| SCHEMBL7098415 | 0.92 | JAK2 (0.37) | RIPK1HDAC4JAK2NTRK1 | |
| SCHEMBL7102968 | 0.92 | JAK2 (0.37) | RIPK1HDAC4JAK2NTRK1 | |
| SCHEMBL7097553 | 0.90 | RIPK1 (0.36) | RIPK1HDAC4JAK2NTRK1 | |
| SCHEMBL7097829 | 0.90 | RIPK1 (0.36) | RIPK1HDAC4JAK2NTRK1 | |
| SCHEMBL7098836 | 0.86 | RIPK1 (0.39) | RIPK1HDAC4JAK2NTRK1 | |
| SCHEMBL7103958 | 0.82 | PROKR1 (0.36) | HDAC4 | |
| SCHEMBL7484205 | 0.82 | PROKR1 (0.36) | HDAC4 | |
| SCHEMBL7487273 | 0.80 | CHRNB2 (0.39) | TLR7 | |
| SCHEMBL7097543 | 0.80 | CHRNB2 (0.39) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003500402-A | — | — | 2003-01-07 | — | — | JP | claimed |
| EP-1178982-A1 | HETEROCYCLIC SUBSTITUTED AMINOAZACYCLES USEFUL AS CENTRAL NERVOUS SYSTEM AGENTS | ABBOTT LABORATORIES (US) | 2002-02-13 | — | — | EP | claimed |
| WO-2000071534-A1 | HETEROCYCLIC SUBSTITUTED AMINOAZACYCLES USEFUL AS CENTRAL NERVOUS SYSTEM AGENTS | ABBOTT LABORATORIES (US) | 2000-11-30 | — | — | WO | claimed |