Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | YAP1 | P46937 | 11/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100727 | 0.93 | PPARG (0.55) | PPARGYAP1 | |
| SCHEMBL7100726 | 0.93 | PPARG (0.55) | PPARGYAP1 | |
| SCHEMBL7103992 | 0.91 | YAP1 (0.58) | PPARGYAP1CYP3A4TSHRALDH1A1 | |
| SCHEMBL7103995 | 0.91 | YAP1 (0.58) | PPARGYAP1CYP3A4TSHRALDH1A1 | |
| SCHEMBL7102219 | 0.88 | PPARG (0.54) | PPARGYAP1CYP3A4TSHRALDH1A1 | |
| SCHEMBL7102218 | 0.88 | PPARG (0.54) | PPARGYAP1CYP3A4TSHRALDH1A1 | |
| SCHEMBL7098791 | 0.81 | ITGA4 (0.60) | — | |
| SCHEMBL7098794 | 0.81 | ITGA4 (0.60) | — | |
| SCHEMBL7101959 | 0.81 | PPARG (0.54) | PPARGYAP1MEN1KMT2A | |
| SCHEMBL7101955 | 0.81 | PPARG (0.54) | PPARGYAP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | disclosed |