Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 13/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103995 | 1.00 | YAP1 (0.58) | YAP1PPARGACEMEN1ALDH1A1 | |
| SCHEMBL7103986 | 0.91 | PPARG (0.55) | YAP1PPARGMEN1ALDH1A1KMT2A | |
| SCHEMBL7100727 | 0.85 | PPARG (0.55) | YAP1PPARGACE | |
| SCHEMBL7100726 | 0.85 | PPARG (0.55) | YAP1PPARGACE | |
| SCHEMBL7102219 | 0.83 | PPARG (0.54) | YAP1PPARGMEN1ALDH1A1KMT2A | |
| SCHEMBL7102218 | 0.83 | PPARG (0.54) | YAP1PPARGMEN1ALDH1A1KMT2A | |
| SCHEMBL6161729 | 0.79 | BCL2 (0.64) | YAP1PPARGMEN1ALDH1A1KMT2A | |
| SCHEMBL3500186 | 0.79 | BCL2 (0.64) | YAP1PPARGMEN1ALDH1A1KMT2A | |
| SCHEMBL3350988 | 0.79 | BCL2 (0.64) | YAP1PPARGMEN1ALDH1A1KMT2A | |
| SCHEMBL7101955 | 0.77 | PPARG (0.54) | YAP1PPARGACEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-20030130349-A1 | Inhibitors of alpha 4beta1 mediated cell adhesion | TANABE SEIYAKU CO., LTD. | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130349-A1 | Inhibitors of alpha 4beta1 mediated cell adhesion | VCAM1, ICAM1, ITGB1 | YAP1 2670/4885PPARG 4759/4885ACE 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.